The same thing applies to the greeting, How Do You Do?   

In both of these greetings/questions you are presented an opportunity to speak.   What you speak is extremely important.   

Death and life are in the power of the tongue: and they that love it shall eat the fruit thereof. Pro 18:21 God created us in His Image (Gen 1:27).      He gave us the Powers of Imagination and Speech.      Just as God is Life He has given us Life.     Just as God's Words accomplish His Will so our words have the Power to accomplish our Will.      When God Speaks He Speaks in Faith, knowing that what He has Spoken will be (Isa 55:11).      The Holy Spirit who is the Power of God gives substance to His Words (Gen 1:2 Zec 4:6).      Jesus made it possible for us to become New Spirit beings (Joh 3:5) as God is Spirit (Joh 4:24).      Jesus made it possible for our Body to be Filled with the Holy Spirit (Joh 20:22 Act 2:4).      As Spirit Filled New Creatures we are One with the Father (Joh 17:11) and therefore have His Will as our Will (Rom 12:2).      In this mature state of Faith and Relationship we can Speak the Words of God and see the Will of God manifested just as our Lord Jesus did (Joh 14:12).

We were made in the image of God.   This does not just speak to our nature but also to our abilities - or at least, our potential.   

And the Lord said, Let there be light: and there was light. Gen 1:3 The Lord defines light and goodness.     In so doing, He defined darkness and evil.      Jesus is the Light that the Holy Spirit brought forth.     He is the Soul Of God that conceptualized Light, spoke the Light and then manifested it in human form.

And the Lord said, Let there be a firmament in the midst of the waters, and let it divide the waters from the waters. Gen 1:6 Once the spiritual nature of that which He will create is defined, He moves forward with the physical universe.      The firmament is the atmosphere, stratosphere, ionosphere and outer space.

And the Lord said, Let the earth bring forth grass, the herb yielding seed, and the fruit tree yielding fruit after his kind, whose seed is in itself, upon the earth: and it was so. Gen 1:11 All life produces after its kind.     This message is to inform us that the Lord produces after His kind.     We are Children Of The Lord and so we are like Him.

And the Lord said, Let there be lights in the firmament of the heaven to divide the day from the night; and let them be for signs, and for seasons, and for days, and years: Gen 1:14 Since God would later create man in time, He provided the means by which time would be measured.

And the Lord said, Let the waters bring forth abundantly the moving creature that has life, and fowl that may fly above the earth in the open firmament of heaven. Gen 1:20 Water in the rivers, lakes and oceans provide the life for aguatic plants and animals.

And the Lord said, Let the earth bring forth the living creature after his kind, cattle, and creeping thing, and beast of the earth after his kind: and it was so. Gen 1:24 All life produces after its kind.     This message is to inform us that the Lord produces after His kind.     We are children of the Lord and so like Him.

Everything the Lord created was imagined and then spoken into existence.   

He has given us the powers of
   → imagination
   → speech
   → creativity
   → Free Will

What we do with these powers determines the quantity and quality of life that we experience.   

A good man out of the good treasure of his heart brings forth that which is good; and an evil man out of the evil treasure of his heart brings forth that which is evil: for of the abundance of the heart his mouth speaks. Luk 6:45 The Lord is good and anyone who aspires to be good must be filled with the Lord the Holy Spirit.     He it is that manifests good in us.     Phi 2:13 Our hearts must be transformed by the power of the Word and the Holy Spirit.

Since what we say issues from our heart we must check the orientation of our hearts.   

Did you know that God Himself oriented His heart?   Yes, God has Free Will.   He chose to be love, to be good, to be gracious.   Since He is omnipotent, He has the power to eternally enforce that choice.   

We are not omnipotent.   

We need His Word (thoughts) and His Spirit (power) in order to stand, to think and to speak consistently with Him.   

But when we are born we are virtually independent of the thoughts and power of God.   There is just a tiny awareness of Him, but it is by no means over-powering.   
   → we must desire Him
   → we must search for Him
   → we must hear Him
   → we must believe Him
   → we must receive Him
   → we must submit to Him
   → we must be filled with Him
   → we must be transformed by Him

Until a person is transformed by the Truth of the Lord Jesus Christ what he imagines, what says and what he does will invariably produce death instead of life.   

So, when you greet a person with What Do You Say?   listen to their response.   It will give you an indication of
   → their hope or fear
   → their health or sickness
   → their joy or sadness
   → their strength or weakness

In short, it reveals the state of their relationship with the Lord Jesus Christ.   

Our reaction to their response should be
   → to rejoice with them if they are rejoicing,
   → to mourn with them if they are mourning,
   → to encourage them in the Lord and
   → to pray with them if they have a need.   

Some will say, I had rather just ignore their response and continue thinking about what was on my mind and what I needed to be doing.   

And most people do exactly that.   The reason is that they are weak and searching themselves.   

We can only give what we have.   

If you feel inadequate to respond as our Lord Jesus responded to those He encountered, you simply need more of Him - more of His Word and more integration into His Holy Spirit.   

Believe you not that I am in the Father, and the Father in me?     the words that I speak unto you I speak not of myself: but the Father that dwells in me, he does the works. Joh 14:10 How can Jesus be in the Father and the Father be in Him?      Understand who the Father is.     He is a Spirit.     He is the Holy Spirit.     The Holy Spirit fills the universe and beyond.     But He birthed the body of Jesus and annointed Him to be Messiah - He filled the body of Jesus.      Jesus spoke what the Holy Spirit inspired Him to speak.     Jesus reached out to heal and deliver those whom the Holy Spirit empowered Him to bless.      Just as the disciples and others of Jesus' day could not look past the physical form of Jesus and see the Father, likewise today, people cannot see past our physical form to see the Father in us.      What is even worse is that many of us cannot look past our own physical form to realize Christ in us the expectation of the Father's glory being manifested in and through us.      Greater works shall we do because the Father has made His abode in us.     We are filled with the Holy Spirit.      Father is a role.     It is not the name of a being.     The name of the Father is Christ Jesus.     (For that matter, the name of the Holy Spirit is Christ Jesus).     But Jesus was clarifying how He, as a man, was able to do what He did and say what He said.      The Holy Spirit is the Father of Jesus.     He is the one who impregnated Mary.     He is the One who inspires and implements the Word.      So, Jesus being the Word speaks and interacts with those in the Physical Realm, while the Holy Spirit from the Spirit Realm ( Heaven) inspires Jesus to speak and then performs the works that Jesus does.      The Holy Spirit and the Word are One.     You cannot separate them.     If you try to you will either have the Word or the Power and neither will be effective.     The Word speaks the purpose, while the Power achieves the purpose.     The Holy Spirit and Word are inseparable.

Jesus spoke both life and death in total agreement with His Holy Spirit because He was and is the Spirit Soul And Body of God.   

We have been given His Holy Spirit.   We each have our own body.   We each have our own soul.   Our challenge is for our minds to be transformed to the Mind Of Christ and for our bodies to be submitted as living sacrifices in His service.   

If we live in the Holy Spirit, let us also walk in the Holy Spirit. Gal 5:25 The Holy Spirit is the Spirit Of Christ Jesus.     When we are In Christ, we are in His Holy Spirit and His Holy Spirit is in us.      Since we have New Life by the New Spirit it only makes sense for us to walk in the Spirit.     Walking implies that our physical lives are different - that we talk differently, that we do differently.      Jesus is fully man and He is fully God because His Spirit is the Holy Spirit.     He was not born with the Sin Nature that the rest of us were.     But He had to learn submission to the Father.     When He was baptised with the Holy Spirit He was empowered to walk in the Spirit.     He went to the wilderness fasting and praying until He was totally conformed to the will of the Father.     When He left the wilderness He was prepared to walk in the Spirit.      To walk in the Spirit is to believe and appropriate the promises of the Lord while fellowshipping with Him in the Holy Spirit.

Our Lord wants to to manifest His character wherever we go.   That character is most powerfully effected through the words that we speak.   

Speak life and live.   Speak life and promote it in others.   

It is the spirit that quickens; the flesh profits nothing: the words that I speak unto you, they are spirit, and they are life. Joh 6:63 This is profound Truth!      The Holy Spirit makes us alive and keeps us alive.      The flesh does not help anything.     It is sustained by the Spirit.      Our life comes from the Word Of The Lord which issues from the Holy Spirit.      But, The Word/HolySpirit wait for us to release the power.      We do so by faith in the authority of Christ and His Word.      The Word and Spirit is One.     Jesus is the Word who speaks according to His Holy Spirit.